Pantherna Therapeutics GmbH and PROVIREX Genome Editing Therapies GmbH are developing lipid-based delivery systems for mRNA-directed genome editing of lymphocytes for the treatment of HIV and other life-threatening persistent viral diseases

Pantherna Therapeutics and PROVIREX have entered into a research collaboration. Based on Pantherna’s proprietary PTXxLNP delivery technology both parties will develop and evaluate novel lipid-based mRNA formulations for the transfection of CD4+ lymphocytes. PTXxLNP is a promising candidate for the non-viral delivery of PROVIREX’s proprietary antiviral genome editing tool Brec1.